Bill & Melinda Gates Foundation

Reflecting Back on a Grand Decade of Innovation

Nearly fifteen years ago, the Bill & Melinda Gates Foundation launched Grand Challenges—a landmark initiative to fund promising early-stage scientific innovations that could prevent, treat and cure diseases in the developing world.

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Grand Challenges: Fueling Innovation in Global Health and Development

Nearly fifteen years ago, the Bill & Melinda Gates Foundation launched Grand Challenges—a landmark initiative to fund promising early-stage scientific innovations that could prevent, treat and cure diseases in the developing world. As part of the launch of Grand Challenges, we, along with partners at the Wellcome Trust, the Foundation for the National Institutes of Health and the Canadian Institute of Health Research, invested nearly half a billion dollars to kickstart 44 ambitious projects. In the more than a decade that has followed the initial 2005 investments, Grand Challenges has expanded to represent a growing network of independent, but collaborating, national Grand Challenge programs with investments in 87 countries.

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Innovation: Expanding the Fight Against Malaria

When your goal is just to reduce illness and death caused by malaria, you’re likely to focus most of your energy on Plasmodium falciparum – the deadliest and most common parasite behind the disease. But when you’re trying to end malaria for good – eradicate it from the face of our planet – you have to tackle malaria in all its forms, including P. vivax. This presents additional challenges that require innovation.

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From Assessing Family Planning Needs to Accelerating Drug Development for Childhood Diarrhea - Big Ideas from Grand Challenges Explorations Latest Awardees

Big Ideas from Grand Challenges Explorations Latest Awardees

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Innovation: Taking the Neglect out of Neglected Disease

Chances are you’ve never heard of onchocerciasis. Sometimes it’s known by the nickname “river blindness,” but you’ve probably never heard of that, either. Unfortunately, almost 40 million people suffer from it.

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