Bill & Melinda Gates Foundation

Reflecting Back on a Grand Decade of Innovation

Nearly fifteen years ago, the Bill & Melinda Gates Foundation launched Grand Challenges—a landmark initiative to fund promising early-stage scientific innovations that could prevent, treat and cure diseases in the developing world.

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Grand Challenges: Fueling Innovation in Global Health and Development

Nearly fifteen years ago, the Bill & Melinda Gates Foundation launched Grand Challenges—a landmark initiative to fund promising early-stage scientific innovations that could prevent, treat and cure diseases in the developing world. As part of the launch of Grand Challenges, we, along with partners at the Wellcome Trust, the Foundation for the National Institutes of Health and the Canadian Institute of Health Research, invested nearly half a billion dollars to kickstart 44 ambitious projects. In the more than a decade that has followed the initial 2005 investments, Grand Challenges has expanded to represent a growing network of independent, but collaborating, national Grand Challenge programs with investments in 87 countries.

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Innovation: How a 50-Year-Old Drop of Blood Helps Solve an Urgent Global Health Challenge

In high-income countries, babies born preterm (before 37 weeks in the womb) are at increased risk for complications, but many of these complications can be treated effectively with readily available tools, including ventilators to help preterm newborns breathe, IV lines to supply nutrition and antibiotics to treat sepsis.

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Innovation: Expanding the Fight Against Malaria

When your goal is just to reduce illness and death caused by malaria, you’re likely to focus most of your energy on Plasmodium falciparum – the deadliest and most common parasite behind the disease. But when you’re trying to end malaria for good – eradicate it from the face of our planet – you have to tackle malaria in all its forms, including P. vivax. This presents additional challenges that require innovation.

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5 Wearable & Sensor Devices that Save Lives

Finding solutions to maternal and newborn mortality is a challenge that is both simple and complex. Simple because we know most direct causes of death. For example, we know that too many mothers die from postpartum hemorrhage, and preterm newborns often die because of infection. The complexity comes when we try to answer these questions for program implementation

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